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Saturday, June 23, 2012
Friday, June 22, 2012
HBT: Cespedes' walk-off HR helps A's sweep Dodgers
An ugly series for the Dodgers had an especially ugly ending Thursday, with Yoenis Cespedes hitting a walkoff homer in the bottom of the ninth to give the A?s a sweep in Oakland.
Josh Lindblom, one of the NL?s best setup men this season, had a terrible ninth today. He walked Coco Crisp to start the inning and then allowed him to advance with a wild pitch. Jemile Weeks then dropped down the bunt everyone in the ballpark knew was coming, yet Lindblom, after picking it up, turned and looked to fire to third base with no one standing there. Juan Uribe was drawn way in on the play, and even had Uribe been back, it was a good enough bunt with a speedy baserunner that Crisp was likely to be safe anyway.
That made it first and third with none out for Cespedes. Had things gone as planned and the sacrifice been successful, Cespedes almost certainly would have been walked to set up the double play. As it was, the A?s pitched to him, and he ripped a line drive that barely stayed to the right of the foul pole in left, giving the A?s a 4-1 win.
Much credit should go to Travis Blackley. Coming off his first win in eight years last week against the Padres, Blackley matched Clayton Kershaw pitch for pitch in this one. Both threw eight innings and allowed one run on three hits. Kershaw struck out seven and walked two. Blackley fanned six and walked none.
Meanwhile, the Dodgers have to be wondering where their offense went. Despite having the DH available, they scored just two runs in being swept. Leadoff man Dee Gordon went without a hit or a walk for the third straight game today, yet still managed to get caught stealing (he reached on a fielder?s choice in the ninth). $85 million outfielder Andre Ethier is hitting .171 in 70 at-bats this month. They actually used Ivan De Jesus ? a utilityman who hadn?t started a game in three weeks ? as their DH today.
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Rangers recovering 1 of their own after fatal fall
A ground support team of climbing rangers heads up the Glacier Basin Trail toward Camp Schurman on the east side of Mount Rainier, Friday, June 22, 2012. They are participating in the operation begun the previous day which rescued a fallen party of climbers near the top of the mountain and resulted in the death by falling of climbing ranger Nick Hall. (AP Photo/The News Tribune, Peter Haley)
A ground support team of climbing rangers heads up the Glacier Basin Trail toward Camp Schurman on the east side of Mount Rainier, Friday, June 22, 2012. They are participating in the operation begun the previous day which rescued a fallen party of climbers near the top of the mountain and resulted in the death by falling of climbing ranger Nick Hall. (AP Photo/The News Tribune, Peter Haley)
FILE - The west entrance to Mount Rainier National Park is shown in this Jan. 1, 2012 file photo taken in Washington State. A Mount Rainier ranger slid more than 3,000 feet to his death Thursday June 21, 2012 as he helped in efforts to rescue four injured climbers who fell on a glacier, a National Park Service spokesman said. (AP Photo/Ted S. Warren, File)
SEATTLE (AP) ? The family of a Mount Rainier National Park ranger who died while helping rescue four climbers both grieved and celebrated his life Friday, as authorities faced the grim task of recovering the body of one of their own.
Nick Hall, 33, slid more than 3,000 feet to his death Thursday as he was helping evacuate climbers from a crevasse by helicopter near the summit of the 14,411-foot mountain.
Hall, a four-year veteran of the park's climbing program, came from a family of EMTs who aided soldiers in Iraq and car crash victims in his small hometown of Patten, Maine. He was not married and had no children.
His father, Carter Hall, recalled his son as a loner when he was a child, but flourished in high school through a shared love of the wilderness.
"For good and bad, it was my influence of the outdoors," Hall told The Associated Press in a call from his Maine home, his voice breaking.
A Chinook helicopter from Joint Base Lewis-McChord removed three of the four climbers from Waco, Texas, and rangers stayed overnight with the fourth person. Poor weather complicated rescue and recovery efforts Friday, with snow falling above 10,000 feet, the level where Hall landed after the slide.
The remaining climber and four rangers started down the mountain early Friday and should be able to walk out unaided, but park officials still hoped a helicopter would be able to pick her up and also recover Hall's body, park spokesman Kevin Bacher said.
Visibility remained poor Friday afternoon, but rangers were hoping for a break to allow a flight, said spokeswoman Brandi Stewart.
The park withheld the names of the Texas climbers until their families were notified.
They had reached the summit and were on their way down, roped together, when two women fell into the crevasse on Emmons Glacier. Two men were able to stop the group, and one called for help by cellphone.
Rangers and the helicopter responded to the site at the 13,700-foot level. A helicopter airlifted the three to Madigan Army Medical Center at the military base near Tacoma, where they were hospitalized in fair condition Friday, said spokesman Jay Ebbeson.
The climbers were bruised with possible broken bones, Bacher said.
Hall had helped put three climbers into the helicopter when he fell. The park is investigating exactly how he fell, Bacher said.
"We don't want what happened to Nick to happen again," he said. "There's no urgency today; nobody's life is at risk today. Let's take it slow and make sure nobody else is hurt."
"We're a very small team and particularly the climbing team ? basically 15 people under the climbing foreman," said Bacher, who also is a ranger. "And they work very close together and train close together and depend on each other for their lives and become very close."
Hall's family said they were proud of his involvement in mountain rescues, and hoped that his death will draw attention to the profession's dangers.
Hall's father is a volunteer firefighter and EMT in Patten, and his older brother, Aaron, served in the National Guard as an EMT in Iraq. Aaron Hall celebrated his birthday on the day his brother died on the mountain.
Nick Hall had worked as an avalanche forecaster at Yellowstone National Park and as an emergency medical responder for the ski patrol at Washington's Stevens Pass Ski Area, his father said.
When he spoke to him about risks, Carter Hall said, his son responded that dying by heart attack "was also a risk in life."
Hall was the second Mount Rainier National Park ranger to die this year. Margaret Anderson was fatally shot on New Year's Day as she tried to stop a suspect in a Seattle shooting who drove through a tire-chain checkpoint. Benjamin Colton Barnes, 24, was found dead the next day in the snow.
Rescuers are still looking for four other people ? two climbers and two campers ? who disappeared on the mountain in January. "We're keeping our eyes out for them as the snow melts out," Bacher said.
About 10,000 climbers attempt to reach the summit of the volcano about 85 miles southeast of Seattle each year and about half make it, he said.
___
Dininny contributed to this story from Yakima, Wash.
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Jobless claims edge lower, remain elevated
By Patrick Rizzo
New claims for unemployment benefits declined slightly?in the latest week, but remain at levels which?raise concerns that employers are gradually reducing staff in the face of economic uncertainty.
The Labor Department reported Thursday that new jobless claims dropped a seasonally-adjusted 2,000 to 387,000 from a upwardly revised 389,000 the prior week. Economists polled by Reuters had forecast claims falling to 380,000 last week.
The four-week moving average, considered a more accurate gauge of labor market conditions, surged 3,500 to 386,250, which is a six-month high.
"This confirms the weak labor market we have. This is another disappointing number," Wells Fargo senior economist Sam Bullard told Reuters.
The job market has been struggling recently as employers face a slew of uncertainties, including a stumbling U.S. recovery, fiscal deadlock in Washington and a financial crisis in Europe.
The Federal Reserve?warned Wednesday that businesses had slowed hiring. The central bank ratcheted down its projections for economic growth in 2012 and extended a program known as "Operation Twist" aimed at pushing down long-term interest rates?to aid the economy.
At a press conference Wednesday afternoon, Fed Chairman Ben Bernanke said?there had been a great deal of new developments since the Fed?s last meeting in April and that a lot of the incoming data were ?disappointing.???
"There's been a very dramatic decrease in the numbers of hires and there's been a decrease in the numbers of quits," says Edward Lazear, Stanford University economics professor, providing perspective on why hiring levels are falling.
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Thursday, June 21, 2012
Study explains functional links between autism and genes
Thursday, June 21, 2012
A pioneering report of genome-wide gene expression in autism spectrum disorders (ASDs) finds genetic changes that help explain why one person has an ASD and another does not. The study, published by Cell Press on June 21 in The American Journal of Human Genetics, pinpoints ASD risk factors by comparing changes in gene expression with DNA mutation data in the same individuals. This innovative approach is likely to pave the way for future personalized medicine, not just for ASD but also for any disease with a genetic component.
ASDs are a heterogeneous group of developmental conditions characterized by social deficits, difficulty communicating, and repetitive behaviors. ASDs are thought to be highly heritable, meaning that they run in families. However, the genetics of autism are complex.
Researchers have found rare changes in the number of copies of defined genetic regions that associate with ASD. Although there are some hot-spot regions containing these alterations, very few genetic changes are exactly alike. Similarly, no two autistic people share the exact same symptoms. To discover how these genetic changes might affect gene transcription and, thus, the presentation of the disorder, Rui Luo, a graduate student in the Geschwind lab at UCLA, studied 244 families in which one child (the proband) was affected with an ASD and one was not.
In addition to identifying several potential new regions where copy-number variants (CNVs) are associated with ASDs, Geschwind's team found genes within these regions to be significantly misregulated in ASD children compared with their unaffected siblings. "Strikingly, we observed a higher incidence of haploinsufficient genes in the rare CNVs in probands than in those of siblings, strongly indicating a functional impact of these CNVs on expression," says Geschwind. Haploinsuffiency occurs when only one copy of a gene is functional; the result is that the body cannot produce a normal amount of protein. The researchers also found a significant enrichment of misexpressed genes in neural-related pathways in ASD children. Previous research has found that these pathways include other genetic variants associated with autism, which Geschwind explains further legitimizes the present findings.
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Cell Press: http://www.cellpress.com
Thanks to Cell Press for this article.
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Procter & Gamble cuts 4Q profit, revenue outlook
FILE-In this Jan. 25, 2011, file photo, flags from several countries that Procter & Gamble Co. does business in fly outside one of P&G's corporate headquarters buildings in Cincinnati. Procter & Gamble Co. on Wednesday, June 20, 2012, lowered its fourth-quarter earnings and revenue forecasts, hurt by unfavorable foreign exchange rates, continued slow growth in developed markets and a slowdown of growth in China. (AP Photo/Al Behrman, File)
FILE-In this Jan. 25, 2011, file photo, flags from several countries that Procter & Gamble Co. does business in fly outside one of P&G's corporate headquarters buildings in Cincinnati. Procter & Gamble Co. on Wednesday, June 20, 2012, lowered its fourth-quarter earnings and revenue forecasts, hurt by unfavorable foreign exchange rates, continued slow growth in developed markets and a slowdown of growth in China. (AP Photo/Al Behrman, File)
FILE - This Aug. 2, 2010, file photo, shows the Procter & Gamble Co. headquarters building in Cincinnati.. Procter & Gamble Co. on Wednesday, June 20, 2012, lowered its fourth-quarter earnings and revenue forecasts, hurt by unfavorable foreign exchange rates, continued slow growth in developed markets and a slowdown of growth in China. (AP Photo/Al Behrman, File)
NEW YORK (AP) ? Procter & Gamble Co. on Wednesday lowered its fourth-quarter earnings and revenue forecasts, the latest company to sound warning bells about slowing global economic growth.
P&G, which makes an array of everyday goods ranging from Tide detergent to Gillette razors, said it is cutting the forecast because of unfavorable foreign exchange rates, continued slow growth in developed markets and a slowdown of growth in China.
Many U.S. companies have looked to emerging markets as economic growth in North America and Europe has slowed. But P&G's and others' warnings show that expanding abroad is a complicated task for even the largest of companies.
Earlier this month McDonald's said economic volatility, particularly in Asia, is pressuring its second-quarter results. Package delivery company FedEx Corp. on Tuesday said the slowing global economy is expected to crimp its growth over the next 12 months. Its rival UPS in April similarly said slowing Asian shipments hurt quarterly results.
And a wide range of companies including software maker Adobe Systems Inc., medical device maker Synergetics USA and industrial products maker Actuant Inc. have said uncertainty in Europe and slower growth in Asia are hurting.
A few months ago, Europe's economy seemed more positive, Moody's Chief Economist John Lonski said. But that view has darkened in recent months as uncertainty over debt crises in countries such as Spain and Greece dragged on longer than expected. That in turn has led to a slowdown in emerging markets such as Brazil, India and China.
"Global growth is slower than anticipated," he said. "And though it's a stretch to predict the imminence of a global recession, the worldwide slowdown has been great enough to prompt downward revisions of revenue forecasts by multinational corporations."
P&G's cut, announced during a presentation at a Deutsche Bank Global Consumer conference in Paris, is its second in three months. The company is trying to balance growth in emerging markets, which make up about 30 percent of its sales, with the realities of an uncertain global economy and its own executional problems that have led to lackluster market share growth.
Last month P&G said it was rethinking overseas expansion and would focus on its biggest and most profitable markets abroad.
On Wednesday, CEO Bob McDonald reiterated that strategy as well as the company's cost-cutting program, aimed at saving $10 billion by fiscal 2016.
"We are making the necessary adjustments to our growth strategy to increase focus on our core business and to achieve more balanced growth across geographies, product categories and the top and bottom lines," he said in a statement accompanying the presentation.
The world's largest consumer products company said it expects adjusted fourth-quarter earnings between 75 cents and 79 cents per share, down from its previous estimate of 79 cents to 85 cents per share.
Revenue is anticipated to drop 1 percent to 2 percent compared with a prior outlook for a 1 percent to 2 percent increase. The new guidance implies revenue in a range of $20.45 billion to $20.66 billion.
Analysts polled by FactSet foresee earnings of 82 cents per share on revenue of $20.62 billion.
P&G reiterated a plan announced last month that it will prioritize investments in its biggest product innovations, its biggest and most profitable markets and its biggest emerging countries. It also plans to keep investing in new markets.
For fiscal 2013, Cincinnati-based P&G expects adjusted earnings to be up by a mid-to-high single digits percentage rate. The company said it will give an update to the projection when it reports its fiscal 2012 results on Aug. 3.
Its shares fell $1.82, or 2.93 percent, to close at $60.39 Wednesday. Its shares are down 11 percent since peaking for the past year at $67.95 in mid-March. They traded as low as $57.56 last August.
Citi Investment Research analyst Wendy Nicholson said P&G's struggle with market share growth is "discouraging," but said there were some positives in the presentation.
"P&G is clearly saying 'no excuses' and adopting a more aggressive stance about taking responsibility for and fixing their problems," she wrote in a note to investors.
Also on Wednesday, the company reaffirmed its restructuring plan, which involves cutting 5,700 jobs by the end of fiscal 2013 and saving $10 billion by the end of the fiscal 2016.
Like many other consumer products companies, P&G has also been raising prices to deal with higher costs for materials like pulp, fuel and packaging. But in April, P&G said it was rolling back prices in six categories: powdered laundry detergent in the U.S., laundry products in Mexico and the U.K., and North American oral care, dish care and blades and razors. Aside from those categories, other price increases have remained in place.
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